Morphology-to-molecule matching (Anthropic)
Models match four sets of multi-channel liver cell images to the four shuffled molecule and dose treatments that produced them.
Built with Axiom Bio from its in-vitro liver assay data.
- Made by
- Anthropic (with Axiom Bio)
- Released
- September 2026
- Kind
- Research science
- Level
- Expert
- Scored
- Checked automatically
- Answers
- Short answer
- Tasks
- Kept private
- Strongest model tested
- Claude Opus 5.5 #4 on the capability index
- Last in a system card
- October 2026
- Last model added
- October 2026
Claude Opus 5.5 leads with 34%
Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.
- 1 Claude Opus 5.5 34%
- 2 Claude Haiku 5.5 25.4%
- 3 Claude Sonnet 5.5 25%
Source: Labs’ model cards
| # | Model | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | Claude Opus 5.5 | 34% | Sep 2026 | Lab model card | |
| 2 | Claude Haiku 5.5 | 25.4% | Oct 2026 | Lab model card | |
| 3 | Claude Sonnet 5.5 | 25% | Sep 2026 | Lab model card |
Number one over time
Lab claims count from the day the card came out, independent runs from the model’s release.
Source: Labs’ model cards
Scores over time
All the scores we have, one dot each, so a model tested at several settings appears more than once.
Source: Labs’ model cards
Labs report it only in system cards
We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark. Some system cards do, below.
3 system cards report it, from 1 lab
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| Oct 7, 2026 | Claude Haiku 5.5 system card | 25.4 | Morphology-to-molecule matching, max effort (8.13.2) | Capabilities |
| Sep 28, 2026 | Claude Sonnet 5.5 system card | 25 | Morphology-to-molecule matching (8.17.3, Figure 8.17.A) | Capabilities |
| Sep 22, 2026 | Claude Opus 5.5 system card | 34 | Morphology-to-molecule matching (Axiom Bio liver assay), max effort (8.17.3) | Capabilities |
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