Catastrophic biology scenario uplift trial (Anthropic)
PhD biologists with model access spend up to 16 hours planning a catastrophic biological scenario. External experts grade uplift and executability.
Human uplift trial. Anthropic reports whether any plan was judged both highly uplifted and credibly executable.
- Made by
- Anthropic
- Kind
- Hazardous knowledge
- Level
- Expert
- Scored
- Graded by people
- Answers
- Open-ended
- Tasks
- Kept private
- Last in a system card
- April 2026
- Last model added
- April 2026
1
System card reports it, from 1 lab
No scores here yet
No lab, leaderboard or Epoch AI run has reported a score for Catastrophic biology scenario uplift trial (Anthropic) yet.
Labs report it only in system cards
We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark. Some system cards do, below.
One system card reports it
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| Apr 7, 2026 | Claude Mythos Preview system card | Catastrophic biology scenario uplift trial, 10 participants, no numeric score. No plan was judged both highly uplifted and likely to succeed (2.2.5.3) | Bio and chem risk |
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