ProtocolQA Open-Ended
Models correct errors in published lab protocols using open-ended questions adapted from LAB-Bench ProtocolQA. Scored as pass@1.
OpenAI open-ended adaptation of the ProtocolQA multiple-choice set.
- Made by
- OpenAI
- Released
- December 2024
- Kind
- Lab protocols
- Level
- Expert
- Scored
- Graded by a model
- Answers
- Short answer
- Tasks
- Kept private
- Strongest model tested
- GPT-6 Astra #3 on the capability index
- Last in a launch post
- November 2026
- Last model added
- November 2026
GPT-6 Cyber leads with 47.2%
Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.
- 47.2 GPT-6 Cyber
- 44.4 GPT-6 Sol
- 44.1 GPT-5.6 Sol
- 44.0 GPT-5.3 Codex
- 42.5 GPT-5.4
- 42.0 GPT-Rosalind-6
- 41.4 GPT-6 Astra
- 40.7 GPT-6.1 Sol
- 40.0 GPT-5.2
- 39.0 GPT-5.2 Codex
- 37.3 GPT-5.5
- 37.0 GPT-5 mini
- 36.7 GPT-5.5 Pro
- 36.7 GPT-5.5 Instant
- 35.0 GPT-5.1-Codex-Max
- 34.9 GPT-6 Luna
- 33.6 GPT-5.4 Mini
- 30.0 o3
- 30.0 GPT-5
- 29.9 GPT-5.6 Luna
- 28.0 OpenAI deep research
- 27.0 o4-mini
- 27.0 gpt-oss-120b
- 24.0 o1
- 23.0 o3-mini
- 18.0 GPT-4.5
- 16.0 gpt-oss-20b
- 1 GPT-6 Cyber 47.2%
- 2 GPT-6 Sol 44.4%
- 3 GPT-5.6 Sol 44.1%
- 4 GPT-5.3 Codex 44%
- 5 GPT-5.4 42.5%
- 6 GPT-Rosalind-6 42%
- 7 GPT-6 Astra 41.4%
- 8 GPT-6.1 Sol 40.7%
- 9 GPT-5.2 40%
- 10 GPT-5.2 Codex 39%
- 11 GPT-5.5 37.3%
- 12 GPT-5 mini 37%
- 13 GPT-5.5 Pro 36.7%
- 14 GPT-5.5 Instant 36.7%
- 15 GPT-5.1-Codex-Max 35%
- 16 GPT-6 Luna 34.9%
- 17 GPT-5.4 Mini 33.6%
- 18 o3 30%
- 19 GPT-5 30%
- 20 GPT-5.6 Luna 29.9%
- 21 OpenAI deep research 28%
- 22 o4-mini 27%
- 23 gpt-oss-120b 27%
- 24 o1 24%
- 25 o3-mini 23%
- 26 GPT-4.5 18%
- 27 gpt-oss-20b 16%
Source: Labs’ model cards
| # | Model | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | GPT-6 Cyber | 47.2% | Nov 2026 | Lab model card | |
| 2 | GPT-6 Sol | 44.4% | Sep 2026 | Lab model card | |
| 3 | GPT-5.6 Sol | 44.1% | Aug 2026 | Lab model card | |
| 4 | GPT-5.3 Codex | 44% | Feb 2026 | Lab model card | |
| 5 | GPT-5.4 | 42.5% | Mar 2026 | Lab model card | |
| 6 | GPT-Rosalind-6 | 42% | Oct 2026 | Lab model card | |
| 7 | GPT-6 Astra | 41.4% | Sep 2026 | Lab model card | |
| 8 | GPT-6.1 Sol | 40.7% | Sep 2026 | Lab model card | |
| 9 | GPT-5.2 | 40% | Dec 2025 | Lab model card | |
| 10 | GPT-5.2 Codex | 39% | Dec 2025 | Lab model card | |
| 11 | GPT-5.5 | 37.3% | Apr 2026 | Lab model card | |
| 12 | GPT-5 mini | 37% | Aug 2025 | Lab model card | |
| 13 | GPT-5.5 Pro | 36.7% | Apr 2026 | Lab model card | |
| 14 | GPT-5.5 Instant | 36.7% | May 2026 | Lab model card | |
| 15 | GPT-5.1-Codex-Max | 35% | Nov 2025 | Lab model card | |
| 16 | GPT-6 Luna | 34.9% | Sep 2026 | Lab model card | |
| 17 | GPT-5.4 Mini | 33.6% | Mar 2026 | Lab model card | |
| 18 | o3 | 30% | Apr 2025 | Lab model card | |
| 19 | GPT-5 | 30% | Aug 2025 | Lab model card | |
| 20 | GPT-5.6 Luna | 29.9% | Aug 2026 | Lab model card | |
| 21 | OpenAI deep research | 28% | Feb 2025 | Lab model card | |
| 22 | o4-mini | 27% | Apr 2025 | Lab model card | |
| 23 | gpt-oss-120b | 27% | Aug 2025 | Lab model card | |
| 24 | o1 | 24% | Dec 2024 | Lab model card | |
| 25 | o3-mini | 23% | Jan 2025 | Lab model card | |
| 26 | GPT-4.5 | 18% | Feb 2025 | Lab model card | |
| 27 | gpt-oss-20b | 16% | Aug 2025 | Lab model card |
9 models have held number one in labs’ own numbers since its release in December 2024
Lab claims count from the day the card came out, independent runs from the model’s release.
Source: Labs’ model cards
Scores over time
All the scores we have, one dot each, so a model tested at several settings appears more than once.
Source: Labs’ model cards
One lab put it in a launch post in the last six months
Launch posts from every lab that has listed it, one tick per post. Tall colored ticks include it, and short gray ones leave it out.
| Date | Launch post | Score | As the post writes it |
|---|---|---|---|
| Nov 5, 2026 | GPT-6 Cyber | 47.2 | ProtocolQA Open-Ended, standard scoring |
37 system cards report it, from 1 lab
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| Nov 5, 2026 | GPT-6 Cyber system card | 47.2 | ProtocolQA Open-Ended, standard scoring | Bio and chem risk |
| Oct 30, 2026 | GPT-Rosalind-6 system card | 42 | ProtocolQA Open-Ended, pass@1, refusal-adjusted | Bio and chem risk |
| Oct 29, 2026 | GPT-6 Luna system card addendum | 31.8 | ProtocolQA Open-Ended, pass@1 (Table 8) | Bio and chem risk |
| Oct 7, 2026 | GPT-6 Sol system card addendum | 25.6 | ProtocolQA Open-Ended, pass@1 (Table 8) | Bio and chem risk |
| Oct 7, 2026 | GPT-6 Luna system card addendum | 34.6 | ProtocolQA Open-Ended, pass@1 (Table 8) | Bio and chem risk |
| Sep 29, 2026 | GPT-6.1 Sol system card addendum | 40.7 | ProtocolQA Open-Ended, refusal-adjusted pass@1 (9.1.1.1) | Bio and chem risk |
| Sep 22, 2026 | GPT-6 Sol system card | 44.4 | ProtocolQA Open-Ended, pass@1 (Table 33, A.8.1.1.1) | Bio and chem risk |
| Sep 22, 2026 | GPT-6 Luna system card | 34.9 | ProtocolQA Open-Ended, pass@1 (Table 33, A.8.1.1.1) | Bio and chem risk |
| Sep 3, 2026 | GPT-6 Astra system card | 41.4 | ProtocolQA Open-Ended, pass@1 (refusal-adjusted 45.37%) (10.1.1.1.2) | Bio and chem risk |
| Aug 6, 2026 | GPT-5.6 Sol system card addendum | 44.1 | ProtocolQA Open-Ended, pass@1, printed chart label (Figure 4, 7.1.1.2) | Bio and chem risk |
| Aug 6, 2026 | GPT-5.6 Luna system card addendum | 29.9 | ProtocolQA Open-Ended, pass@1, printed chart label (Figure 4, 7.1.1.2) | Bio and chem risk |
| Jul 9, 2026 | GPT-5.6 Terra system card | ProtocolQA Open-Ended, pass@1 by cost, chart without printed numbers (Figures 24, 25, 9.1.1.2) | Bio and chem risk | |
| Jul 9, 2026 | GPT-5.6 Sol system card | 43.5 | ProtocolQA Open-Ended, pass@1, top score stated in text (9.1.1.2) | Bio and chem risk |
| Jul 9, 2026 | GPT-5.6 Luna system card | ProtocolQA Open-Ended, pass@1 by cost, chart without printed numbers (Figures 24, 25, 9.1.1.2) | Bio and chem risk | |
| Jun 25, 2026 | GPT-5.6 Terra system card | ProtocolQA Open-Ended, pass@1 by cost, chart without printed numbers (Figures 24, 25, 9.1.1.2) | Bio and chem risk | |
| Jun 25, 2026 | GPT-5.6 Sol system card | 43.5 | ProtocolQA Open-Ended, pass@1, top score stated in text (9.1.1.2) | Bio and chem risk |
| Jun 25, 2026 | GPT-5.6 Luna system card | ProtocolQA Open-Ended, pass@1 by cost, chart without printed numbers (Figures 24, 25, 9.1.1.2) | Bio and chem risk | |
| May 4, 2026 | GPT-5.5 Instant system card | 36.7 | ProtocolQA Open-Ended, pass@1, printed chart label (Figure 4, 8.1.1.2) | Bio and chem risk |
| Apr 23, 2026 | GPT-5.5 system card | 37.3 | ProtocolQA Open-Ended, pass@1, printed chart label (Figure 13, 9.1.1.2) | Bio and chem risk |
| Apr 23, 2026 | GPT-5.5 Pro system card | 36.7 | ProtocolQA Open-Ended, pass@1, GPT-5.5 Pro, printed chart label (Figure 13, 9.1.1.2) | Bio and chem risk |
| Mar 17, 2026 | GPT-5.4 Mini system card | 33.6 | ProtocolQA Open-Ended, pass@1 (34.24% counting refusals) (Table 18) | Bio and chem risk |
| Mar 5, 2026 | GPT-5.4 system card | 42.5 | ProtocolQA Open-Ended, pass@1, printed chart label (Figure 9, 5.1.1.2) | Bio and chem risk |
| Feb 5, 2026 | GPT-5.3 Codex system card | 44 | ProtocolQA Open-Ended, pass@1, no browsing, printed chart label (Figure 2, 5.1.1.2) | Bio and chem risk |
| Dec 18, 2025 | GPT-5.2 Codex system card addendum | 39 | ProtocolQA Open-Ended, pass@1, printed chart label (Figure 2, 5.1.1.2) | Bio and chem risk |
| Dec 11, 2025 | GPT-5.2 system card addendum | 40 | ProtocolQA Open-Ended, pass@1, gpt-5.2 browsing, printed chart label (Figure 6) | Bio and chem risk |
| Nov 18, 2025 | GPT-5.1-Codex-Max system card | 35 | ProtocolQA Open-Ended, pass@1, printed chart label (39% with refusals counted) (Figure 3, 5.1.1.3) | Bio and chem risk |
| Aug 7, 2025 | GPT-5 system card | 30 | ProtocolQA Open-Ended, pass@1, browsing launch candidate (Figure 11) | Bio and chem risk |
| Aug 7, 2025 | GPT-5 mini system card | 37 | ProtocolQA Open-Ended, pass@1, gpt-5-thinking-mini browsing launch candidate (Figure 11) | Bio and chem risk |
| Aug 5, 2025 | gpt-oss-20b model card | 16 | ProtocolQA Open-Ended, pass@1, gpt-oss 20b browsing launch candidate (Figure 7) | Bio and chem risk |
| Aug 5, 2025 | gpt-oss-120b model card | 27 | ProtocolQA Open-Ended, pass@1, gpt-oss 120b browsing launch candidate (Figure 7) | Bio and chem risk |
| Jul 17, 2025 | ChatGPT agent system card | ProtocolQA Open-Ended, pass@1, chart shows only ChatGPT Agent browsing helpful-only at 40%, no released-model value (Figure 3, 5.1.1.3) | Bio and chem risk | |
| Apr 16, 2025 | o4-mini system card | 27 | ProtocolQA Open-Ended, pass@1, o4-mini no browsing launch candidate, printed chart label (Figure 5) | Bio and chem risk |
| Apr 16, 2025 | o3 system card | 30 | ProtocolQA Open-Ended, pass@1, o3 no browsing launch candidate, printed chart label (Figure 5) | Bio and chem risk |
| Feb 27, 2025 | GPT-4.5 system card | 18 | ProtocolQA Open-Ended, pre- and post-mitigation (4.3.4) | Bio and chem risk |
| Feb 25, 2025 | OpenAI deep research system card | 28 | ProtocolQA Open-Ended, pass@1, post-mitigation with browsing, text and printed chart label (without browsing 27%) (3.4.4) | Bio and chem risk |
| Jan 31, 2025 | o3-mini system card | 23 | ProtocolQA Open-Ended, post-mitigation (5.4.7) | Bio and chem risk |
| Dec 5, 2024 | o1 system card | 24 | ProtocolQA Open-Ended, pass@1, o1 (post-mitigation), printed chart label (5.5.6) | Bio and chem risk |
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