LifeSciBench
Models complete 750 expert-written life science research tasks, often with attached figures, tables, or sequence files. Graded against expert rubrics as score and pass rate.
750 expert-authored tasks over seven workflows and seven biological domains. 1,062 task artifacts, 173 scientist contributors, 19,020 rubric criteria and 453 expert reviewers. Launched 17 June 2026.
- Made by
- OpenAI
- Released
- June 2026
- Kind
- Genomics and life sciences
- Level
- Expert
- Scored
- Graded by a model
- Answers
- Open-ended
- Strongest model tested
- GPT-6 Astra #3 on the capability index
- Last in a launch post
- September 2026
- Last model added
- October 2026
- Scores refreshed
- November 12th, 2026
GPT-Rosalind-6 leads with 61.3%
Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.
GPT-5.5 leads with 51.9% across all independent runs
Best score per model across the official leaderboard, Epoch AI’s own runs and any board Epoch AI copied. Each bar and row names its source.
GPT-Rosalind-6 leads with 61.3%, claims included
Best score per model from every source, including labs’ own numbers and claims Epoch AI collected from reports and papers. Labs pick their own settings, so a claim can beat an independent run of the same model.
- 1 GPT-Rosalind-6 61.3%
- 2 GPT-6 Astra 60.3%
- 3 GPT-5.6 Sol 59.9%
- 4 GPT-5.6 Terra 56%
- 5 GPT-5.6 Luna 51.2%
Source: Labs’ model cards
- 1 GPT-5.5 51.9%
- 2
Gemini 3.1 Pro 51.5% - 3 GPT-5.4 47.9%
- 4 Grok 4.3 39.9%
Source: Official LifeSciBench leaderboard
- 1 GPT-Rosalind-6 61.3%
- 2 GPT-6 Astra 60.3%
- 3 GPT-5.6 Sol 59.9%
- 4 GPT-5.6 Terra 56%
- 5 GPT-5.5 51.9%
- 6 Gemini 3.1 Pro 51.5%
- 7 GPT-5.6 Luna 51.2%
- 8 GPT-5.4 47.9%
- 9 Grok 4.3 39.9%
Sources: Labs’ model cards and official LifeSciBench leaderboard
| # | Model | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | GPT-Rosalind-6 | 61.3% | Oct 2026 | Lab model card | |
| 2 | GPT-6 Astra | 60.3% | Sep 2026 | Lab model card | |
| 3 | GPT-5.6 Sol | 59.9% | Jul 2026 | Lab model card | |
| 4 | GPT-5.6 Terra | 56% | Jul 2026 | Lab model card | |
| 5 | GPT-5.6 Luna | 51.2% | Jul 2026 | Lab model card |
| # | Model | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | GPT-5.5 | 51.9% | Apr 2026 | Official leaderboard | |
| 2 | Gemini 3.1 Pro | 51.5% | Feb 2026 | Official leaderboard | |
| 3 | GPT-5.4 | 47.9% | Mar 2026 | Official leaderboard | |
| 4 | Grok 4.3 | 39.9% | Apr 2026 | Official leaderboard |
| # | Model | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | GPT-Rosalind-6 | 61.3% | Oct 2026 | Lab model card | |
| 2 | GPT-6 Astra | 60.3% | Sep 2026 | Lab model card | |
| 3 | GPT-5.6 Sol | 59.9% | Jul 2026 | Lab model card | |
| 4 | GPT-5.6 Terra | 56% | Jul 2026 | Lab model card | |
| 5 | GPT-5.5 | 51.9% | Apr 2026 | Official leaderboard | |
| 6 | Gemini 3.1 Pro | 51.5% | Feb 2026 | Official leaderboard | |
| 7 | GPT-5.6 Luna | 51.2% | Jul 2026 | Lab model card | |
| 8 | GPT-5.4 | 47.9% | Mar 2026 | Official leaderboard | |
| 9 | Grok 4.3 | 39.9% | Apr 2026 | Official leaderboard |
The benchmark's own leaderboard has 5 entries, 4 of them models we track. Switch the scores above to rank them together.
3 models have held number one in labs’ own numbers since its release in June 2026 Number one over time 4 models have held number one with claims included since its release in June 2026
Lab claims count from the day the card came out, independent runs from the model’s release. We draw one row each for the benchmark’s own leaderboard and what labs claim in their cards.
Sources: Official LifeSciBench leaderboard and labs’ model cards
Scores over time
All the scores we have, one dot each, so a model tested at several settings appears more than once.
Sources: Official LifeSciBench leaderboard and labs’ model cards
One lab put it in a launch post in the last six months
Launch posts from every lab that has listed it, one tick per post. Tall colored ticks include it, and short gray ones leave it out.
| Date | Launch post | Score | As the post writes it |
|---|---|---|---|
| Sep 3, 2026 | GPT-6 Astra | 60.3 | LifeSciBench |
| Jul 9, 2026 | GPT-5.6 Luna | 51.2 | LifeSciBench |
| Jul 9, 2026 | GPT-5.6 Terra | 56 | LifeSciBench |
| Jul 9, 2026 | GPT-5.6 Sol | 59.9 | LifeSciBench (Sol, max) |
One system card reports it
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| Oct 30, 2026 | GPT-Rosalind-6 system card | 61.3 | LifeSciBench Gold, highest reasoning budget, average score | Capabilities |
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