Short-horizon computational biology tasks
Agents perform end-to-end computational tasks related to modifying and engineering biological agents.
In-house Anthropic evaluation. The tasks are not public.
- Made by
- Anthropic
- Released
- May 2025
- Kind
- Hazardous knowledge
- Level
- Expert
- Scored
- Checked automatically
- Answers
- Agent task
- Tasks
- Kept private
- Last in a system card
- February 2026
- Last model added
- February 2026
7
System cards report it, from 1 lab
No scores here yet
No lab, leaderboard or Epoch AI run has reported a score for Short-horizon computational biology tasks yet.
Labs report it only in system cards
We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark. Some system cards do, below.
7 system cards report it, from 1 lab
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| Feb 17, 2026 | Claude Sonnet 4.6 system card | Short-horizon computational biology tasks, crossed lower-bound rule-out thresholds on 3/6 tasks, chart without printed values (Figure 6.2.2.5.A) | Bio and chem risk | |
| Feb 5, 2026 | Claude Opus 4.6 system card | Short-horizon computational biology tasks, 6 tasks with no overall, crossed lower-bound rule-out thresholds on 6/6 tasks, chart without printed values (8.2.4.9, Figure 8.2.4.9.A) | Bio and chem risk | |
| Nov 24, 2025 | Claude Opus 4.5 system card | Short-horizon computational biology tasks, 6 tasks with no overall, crossed lower-bound rule-out thresholds on 3/6 tasks, chart without printed values (7.2.4.6, Figure 7.2.4.6.A) | Bio and chem risk | |
| Sep 29, 2025 | Claude Sonnet 4.5 system card | Short-horizon computational biology tasks, 6 tasks with no overall, helpful-only variant, box plot without printed values. Below the rule-out bar on 3 of 6 tasks (9.2.4.6, Figure 9.2.4.6.A) | Bio and chem risk | |
| Aug 5, 2025 | Claude Opus 4.1 system card addendum | Short-horizon computational biology tasks, six tasks, box plot without printed values. 4 of 6 below the rule-out bar (Figure 6.3.1.1.A) | Bio and chem risk | |
| May 22, 2025 | Claude Sonnet 4 system card | Short-horizon computational biology tasks, six tasks, box plot without printed values. 4 of 6 below the rule-out bar (Figure 7.2.4.9.A) | Bio and chem risk | |
| May 22, 2025 | Claude Opus 4 system card | Short-horizon computational biology tasks, six tasks, box plot without printed values. 4 of 6 below the rule-out bar (Figure 7.2.4.9.A) | Bio and chem risk |
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