Benchmark Almanac

AAV Capsid Packaging Prediction (OpenAI)

GPT-6 Sol 0.53 leads since September 2026
Only in system cards

Models predict packaging scores for held-out AAV capsid variants. Scored as Spearman rank correlation.

OpenAI Critical bio capability evaluation. The Critical threshold is 0.600.

Made by
OpenAI
Released
June 2026
Kind
Genomics and life sciences
Level
Research frontier
Scored
Checked automatically
Answers
Prediction
Tasks
Kept private
Strongest model tested
GPT-6 Astra #3 on the capability index
Last in a system card
October 2026
Last model added
October 2026
7
Models scored in lab cards
8
System cards report it, from 1 lab

GPT-6 Sol leads with 0.53

Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.

  1. 0.53 GPT-6 Sol
  2. 0.53 GPT-6 Luna
  3. 0.53 GPT-5.6 Sol
  4. 0.53 GPT-Rosalind-6
  5. 0.53 GPT-6.1 Terra
  6. 0.53 GPT-6.1 Sol
  7. 0.53 GPT-6 Astra
  1. 1 GPT-6 Sol 0.53
  2. 2 GPT-6 Luna 0.53
  3. 3 GPT-5.6 Sol 0.53
  4. 4 GPT-Rosalind-6 0.53
  5. 5 GPT-6.1 Terra 0.53
  6. 6 GPT-6.1 Sol 0.53
  7. 7 GPT-6 Astra 0.53

Source: Labs’ model cards

#ModelScoreSettingDateSource
1 GPT-6 Sol 0.53 Sep 2026 Lab model card
2 GPT-6 Luna 0.53 Oct 2026 Lab model card
3 GPT-5.6 Sol 0.53 Jun 2026 Lab model card
4 GPT-Rosalind-6 0.53 Oct 2026 Lab model card
5 GPT-6.1 Terra 0.53 Oct 2026 Lab model card
6 GPT-6.1 Sol 0.53 Sep 2026 Lab model card
7 GPT-6 Astra 0.53 Sep 2026 Lab model card

2 models have held number one in labs’ own numbers since its release in June 2026

Lab claims count from the day the card came out, independent runs from the model’s release.

OpenAI
Lab claims 2 leaders
GPT-6 Sol 0.53

Source: Labs’ model cards

Scores over time

All the scores we have, one dot each, so a model tested at several settings appears more than once.

Reported by the lab in its model card
0.53 0.53 0.53 0.53 2026 2027 0.53 0.53 0.53 0.53 2026 2027

Source: Labs’ model cards

Labs report it only in system cards

We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark. Some system cards do, below.

8 system cards report it, from 1 lab

Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.

DateDocumentScoreAs the document writes itSection
Oct 30, 2026 GPT-Rosalind-6 system card 0.529 AAV Capsid Packaging Prediction, Spearman correlation Bio and chem risk
Oct 29, 2026 GPT-6 Luna system card addendum 0.53 AAV Capsid Packaging Prediction, Spearman rank correlation (Table 9) Bio and chem risk
Oct 26, 2026 GPT-6.1 Terra system card addendum 0.528 AAV Capsid Packaging Prediction, Spearman rank correlation (table, 9.0.1.2) Bio and chem risk
Sep 29, 2026 GPT-6.1 Sol system card addendum 0.528 AAV Capsid Packaging Prediction, Spearman rank correlation (9.1.1.2) Bio and chem risk
Sep 22, 2026 GPT-6 Sol system card 0.534 AAV Capsid Packaging Prediction, Spearman rank correlation (Table 34, A.8.1.1.2) Bio and chem risk
Sep 3, 2026 GPT-6 Astra system card 0.528 AAV Capsid Packaging Prediction, Spearman correlation (Table 12) Bio and chem risk
Jul 9, 2026 GPT-5.6 Sol system card 0.529 AAV Capsid Packaging Prediction, Spearman correlation (Table 1, 9.1.1.5) Bio and chem risk
Jun 25, 2026 GPT-5.6 Sol system card 0.529 AAV Capsid Packaging Prediction, Spearman correlation (Table 1, 9.1.1.5) Bio and chem risk

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