LAB-Bench LitQA2
Models answer multiple-choice questions whose answers appear once in recent biology papers. Built to need literature search rather than recall. A LAB-Bench subtask.
199 questions public. PhD researchers score about 70%. FutureHouse PaperQA2 RAG agent matches experts. One of eight LAB-Bench subtasks.
- Made by
- FutureHouse
- Released
- July 2024
- Kind
- Genomics and life sciences
- Level
- Expert
- Scored
- Checked automatically
- Answers
- Multiple choice
- Tasks
- Public, plus a private test set
- Strongest model tested
- Claude 3.5 Sonnet #157 on the capability index
- Last model added
- June 2024
- Scores refreshed
- November 12th, 2026
In the authors’ words
There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and reasoning on textbook-style science questions, but few if any benchmarks are designed to evaluate language model performance on practical tasks required for scientific research, such as literature search, protocol planning, and data analysis. As a step toward building such benchmarks, we introduce the Language Agent Biology Benchmark (LAB-Bench), a broad dataset of over 2,400 multiple choice questions for evaluating AI systems on a range of practical biology research capabilities, including recall and reasoning over literature, interpretation of figures, access and navigation of databases, and comprehension and manipulation of DNA and protein sequences. Importantly, in contrast to previous scientific benchmarks, we expect that an AI system that can achieve consistently high scores on the more difficult LAB-Bench tasks would serve as a useful assistant for researchers in areas such as literature search and molecular cloning. As an initial assessment of the emergent scientific task capabilities of frontier language models, we measure performance of several against our benchmark and report results compared to human expert biology researchers. We will continue to update and expand LAB-Bench over time, and expect it to serve as a useful tool in the development of automated research systems going forward. A public subset of LAB-Bench is available for use at the following URL: https://huggingface.co/datasets/futurehouse/lab-bench
Meta-Llama-3-70B-Instruct tops the leaderboard with 35%
Best score per entry from the benchmark's own leaderboard, read on November 12th, 2026. Where a model ran with several settings or harnesses, we keep its best. Names in gray aren't in our model list: fine-tunes, agent systems, products and older models. They don't count toward leaders. The best model we track is Claude 3 Haiku, at 27%.
The newest model with a score here came out in June 2024, and nobody has tested a newer one. Among the 20 highest-ranked models on the capability index, these have no score yet:
- Claude Fable 5.2
-
Gemini 4 Carbon
- GPT-6 Astra
- Claude Opus 5.5
- and 16 more
- 1 Meta-Llama-3-70B-Instruct 35%
- 2 gpt-4o (snapshot unspecified) 27%
- 3 Claude 3 Haiku 27%
- 4 gpt-4-turbo (snapshot unspecified) 12%
- 5 gemini-1.5-pro-001 10%
- 6 Claude 3 Opus 6.00%
- 7 Claude 3.5 Sonnet 6.00%
Source: Official LAB-Bench LitQA2 leaderboard
| # | Entry | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | Meta-Llama-3-70B-Instruct | 35% | Official leaderboard | ||
| 2 | gpt-4o (snapshot unspecified) | 27% | Official leaderboard | ||
| 3 | Claude 3 Haiku | 27% | Mar 2024 | Official leaderboard | |
| 4 | gpt-4-turbo (snapshot unspecified) | 12% | Official leaderboard | ||
| 5 | gemini-1.5-pro-001 | 10% | Official leaderboard | ||
| 6 | Claude 3 Opus | 6.00% | Feb 2024 | Official leaderboard | |
| 7 | Claude 3.5 Sonnet | 6.00% | Jun 2024 | Official leaderboard |
Number one over time
Lab claims count from the day the card came out, independent runs from the model’s release.
Source: Official LAB-Bench LitQA2 leaderboard
Scores over time
All the scores we have, one dot each, so a model tested at several settings appears more than once.
Source: Official LAB-Bench LitQA2 leaderboard
No lab model card reports it yet
We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark.
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