Benchmark Almanac

LAB-Bench LitQA2

Meta-Llama-3-70B-Instruct 35% tops its leaderboard Claude 3 Haiku 27% leads the models we track
Not in model cards

Models answer multiple-choice questions whose answers appear once in recent biology papers. Built to need literature search rather than recall. A LAB-Bench subtask.

199 questions public. PhD researchers score about 70%. FutureHouse PaperQA2 RAG agent matches experts. One of eight LAB-Bench subtasks.

Made by
FutureHouse
Released
July 2024
Kind
Genomics and life sciences
Level
Expert
Scored
Checked automatically
Answers
Multiple choice
Tasks
Public, plus a private test set
Strongest model tested
Claude 3.5 Sonnet #157 on the capability index
Last model added
June 2024
Scores refreshed
November 12th, 2026

In the authors’ words

There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and reasoning on textbook-style science questions, but few if any benchmarks are designed to evaluate language model performance on practical tasks required for scientific research, such as literature search, protocol planning, and data analysis. As a step toward building such benchmarks, we introduce the Language Agent Biology Benchmark (LAB-Bench), a broad dataset of over 2,400 multiple choice questions for evaluating AI systems on a range of practical biology research capabilities, including recall and reasoning over literature, interpretation of figures, access and navigation of databases, and comprehension and manipulation of DNA and protein sequences. Importantly, in contrast to previous scientific benchmarks, we expect that an AI system that can achieve consistently high scores on the more difficult LAB-Bench tasks would serve as a useful assistant for researchers in areas such as literature search and molecular cloning. As an initial assessment of the emergent scientific task capabilities of frontier language models, we measure performance of several against our benchmark and report results compared to human expert biology researchers. We will continue to update and expand LAB-Bench over time, and expect it to serve as a useful tool in the development of automated research systems going forward. A public subset of LAB-Bench is available for use at the following URL: https://huggingface.co/datasets/futurehouse/lab-bench

Abstract of LAB-Bench: Measuring Capabilities of Language Models for Biology Research (arXiv:2407.10362, CC0)
7
Entries on its own leaderboard, 3 models we track

Meta-Llama-3-70B-Instruct tops the leaderboard with 35%

Best score per entry from the benchmark's own leaderboard, read on November 12th, 2026. Where a model ran with several settings or harnesses, we keep its best. Names in gray aren't in our model list: fine-tunes, agent systems, products and older models. They don't count toward leaders. The best model we track is Claude 3 Haiku, at 27%.

The newest model with a score here came out in June 2024, and nobody has tested a newer one. Among the 20 highest-ranked models on the capability index, these have no score yet:

  1. 1 Meta-Llama-3-70B-Instruct 35%
  2. 2 gpt-4o (snapshot unspecified) 27%
  3. 3 Claude 3 Haiku 27%
  4. 4 gpt-4-turbo (snapshot unspecified) 12%
  5. 5 gemini-1.5-pro-001 10%
  6. 6 Claude 3 Opus 6.00%
  7. 7 Claude 3.5 Sonnet 6.00%

Source: Official LAB-Bench LitQA2 leaderboard

#EntryScoreSettingDateSource
1 Meta-Llama-3-70B-Instruct 35% Official leaderboard
2 gpt-4o (snapshot unspecified) 27% Official leaderboard
3 Claude 3 Haiku 27% Mar 2024 Official leaderboard
4 gpt-4-turbo (snapshot unspecified) 12% Official leaderboard
5 gemini-1.5-pro-001 10% Official leaderboard
6 Claude 3 Opus 6.00% Feb 2024 Official leaderboard
7 Claude 3.5 Sonnet 6.00% Jun 2024 Official leaderboard

Number one over time

Lab claims count from the day the card came out, independent runs from the model’s release.

Anthropic
Own leaderboard Not tested since Jul 2024

Source: Official LAB-Bench LitQA2 leaderboard

Scores over time

All the scores we have, one dot each, so a model tested at several settings appears more than once.

On the benchmark’s own leaderboard Best so far
0% 20% 40% 60% 80% 100% 2024 Near the ceiling (85%) Claude 3 Haiku Claude 3 Opus 0% 20% 40% 60% 80% 100% 2024 Near the ceiling (85%) Claude 3 Haiku Claude 3 Opus

Source: Official LAB-Bench LitQA2 leaderboard

No lab model card reports it yet

We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark.

Versions

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