Benchmark Almanac

Meta BioDesign Proxy

Muse Wonder Full 79.4 leads since October 2026
Only in system cards

Agents complete computational biology design tasks across host-pathogen interaction, protein design and sequence analysis. Aggregate normalized score.

In-house Meta evaluation built with Faculty AI and external experts. The Muse Wonder card reports the average over five tasks in three categories. The tasks are not public.

Made by
Meta + Faculty AI
Kind
Genomics and life sciences
Level
Expert
Scored
Checked automatically
Answers
Agent task
Tasks
Kept private
Strongest model tested
Muse Spark 1.3 #26 on the capability index
Last in a system card
October 2026
Last model added
October 2026
4
Models scored in lab cards
4
System cards report it, from 1 lab

Muse Wonder Full leads with 79.4

Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.

  1. 1 Muse Wonder Full 79.4
  2. 2 Muse Spark 1.3 77.4
  3. 3 Muse Spark 1.1 55.2
  4. 4 Muse Spark 46.2

Source: Labs’ model cards

#ModelScoreSettingDateSource
1 Muse Wonder Full 79.4 Oct 2026 Lab model card
2 Muse Spark 1.3 77.4 Oct 2026 Lab model card
3 Muse Spark 1.1 55.2 Jul 2026 Lab model card
4 Muse Spark 46.2 Jun 2026 Lab model card

3 models have held number one in labs’ own numbers since 2023

Lab claims count from the day the card came out, independent runs from the model’s release.

Meta
Lab claims 3 leaders

Source: Labs’ model cards

Scores over time

All the scores we have, one dot each, so a model tested at several settings appears more than once.

Reported by the lab in its model card
40.0 50.0 60.0 70.0 80.0 2026 2027 40.0 50.0 60.0 70.0 80.0 2026 2027

Source: Labs’ model cards

Labs report it only in system cards

We read the headline results of 522 launch posts from 52 labs, and none of them list this benchmark. Some system cards do, below.

4 system cards report it, from 1 lab

Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.

DateDocumentScoreAs the document writes itSection
Oct 23, 2026 Muse Spark 1.3 system card 77.4 Meta BioDesign Proxy aggregate score over five tasks, Muse Spark 1.3 (API) (Table 1, Figure 4) Bio and chem risk
Oct 12, 2026 Muse Wonder Full model card 79.4 BioDesign Tools Usage (Meta BDT), average over five tasks, printed as 79.4% (CBRN Capability Evaluations table, section 4) Bio and chem risk
Jul 9, 2026 Muse Spark 1.1 system card 55.2 BioDesign Tools (avg) over five tasks, Muse Spark 1.1 Helpful (Table 1, Figure 5) Bio and chem risk
Jun 12, 2026 Muse Spark system card 46.2 BioDesign Tools (avg) over five tasks (Table 1, Figure 5) Bio and chem risk

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